Toxicological Evaluation by Aluminum in Patients Submitted to Hemodialysis with a Focus on Water Quality

Autores

DOI:

https://doi.org/10.70597/ijget.v2i1.393

Palavras-chave:

Water, Aluminum, Hemodialysis, Toxicology

Resumo

Ensuring water quality is extremely important for human health. In hemodialysis, for example, the water is used to produce the dialysis solution, therefore, it is necessary to ensure the chemical and microbiological quality of the water through the monitoring and maintenance from equipments to provide improvements in the life condition of the chronic renal patient, in addition to reducing the hospitalizations and comorbidities. Ensuring the quality of water for human consumption is also extremely important, since water unfit for consumption can lead to the accumulation of inorganic contaminants, especially in people with kidney failure and chronic kidney disease. Considering the importance of ensuring water quality, this work, under development, aims to evaluate the toxicological exposure of the chemical element aluminum in patients who made treatment of hemodialysis in a macroregional hospital unit from the Vale do Mucuri and Jequitinhonha, and correlate her with the water quality.

Referências

Brasil – Agência Nacional de Vigilância Sanitária (ANVISA). Resolução de diretoria colegiada - RDC n° 11, de 13 de março de 2014. Disponível em: <http://portal.anvisa.gov.br/documents/10181/2867923/(1)RDC_11_2014_COMP.pdf/5e552d92-f5734c54-8cab-b06e fa87036e> [Acessado em 12 abril 2018].

Brasil – Ministério da Saúde. Portaria de consolidação nº 5, de 28 de setembro de 2017. Disponível em: <https://www.saude.gov.br/images/pdf/2018/marco/29/PRC-5-Portaria-de-Consolida----o-n---5--de-28desetembro-de-2017.pdf> [Acessado em 12 abril 2018].

Barreto, F.C. and Araújo, S.M.H.A., 2011. Intoxicação alumínica na DRC: Aluminium intoxication in chronic kidney disease. Brazilian Journal of Nephrology, 33(Supl1). https://doi.org/10.1590/S0101-28002011000500006

Loghman-Adham, M., Weber, C.I.K., Ciorciaro, C., Mann, J. and Meier, M., 2012. Detection and management of nephrotoxicity during drug development. Expert Opin Drug Saf, 11(4), pp.581-96. https://doi.org/10.1517/14740338.2012.691964

Thomé, F.S., 2006. Doença renal crônica. In: Barros, E., Manfro, R.C., Thomé, S.F. e Gonçalves, L.F.S. eds, 2006 Nefrologia: Rotinas, diagnóstico e tratamento. 3rd ed. Porto Alegre: Artmed, pp.381-404.

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Publicado

2020-11-01

Como Citar

Duque, P. H. B., Rodrigues, J. L. e Faria, M. C. da S. (2020) “Toxicological Evaluation by Aluminum in Patients Submitted to Hemodialysis with a Focus on Water Quality”, International Journal of Geoscience, Engineering and Technology, 2(1), p. 123–126. doi: 10.70597/ijget.v2i1.393.